Next-generation sequencing refers to non-Sanger-based high-throughput DNA sequencing technologies. Millions or billions of DNA strands can be sequenced in parallel, yielding substantially more throughput and minimizing the need for the fragment-cloning methods that are often used in Sanger sequencing of genomes. A strong trend of developing advanced NGS platforms and related products majorly drives the growth of the NGS market. Other growth factors include increasing applications of NGS, entry of new market players, increasing partnerships & collaborations among market players, and growing incidences of cancer, inherited rare disorders, and pre- and neo-natal disorders.
The technology segment of NGS will be important revenue pockets during the forecast period (2016–2021). By technology, the market is divided into sequencing by synthesis (SBS), ion semiconductor sequencing, sequencing by ligation (SBL), pyrosequencing, and single-molecule real-time (SMRT) sequencing. The sequencing by synthesis (SBS) market is expected to dominate the NGS market by 2021. Development of advanced NGS platforms featuring SBS technology and growing adoption of Illumina NGS systems are the major factors driving the growth of the SBS technology market.
North America is expected to account for the largest share of the global NGS market in 2016. However, the Asia-Pacific market is expected to grow at the highest rate during the forecast period from 2016 to 2021 due to number of factors including improving healthcare infrastructure and favorable government initiatives. The Asia-Pacific market is characterized by a significant focus on R&D activities to broaden the scope of NGS applications, further decrease the cost of NGS products and services, and find effective solutions for data analysis and management. Furthermore, a number of domestic and international market players are increasingly focusing on strengthening their presence in the Asia-Pacific NGS market. In addition to this, regulatory policies in the Asia-Pacific are more adaptive and business-friendly, due to the presence of less-stringent regulations and data requirements. Moreover, increasing competition in mature markets will further compel NGS market players to focus more on emerging markets in the coming years.